Double clicking for site-specific coupling of multiple enzymes.
نویسندگان
چکیده
A method to site-specifically couple multiple enzymes is reported. The approach is based on the site-specific incorporation of a clickable non-natural amino acid into enzymes and two compatible click reactions. The multi-enzyme reaction system exhibited enhanced catalytic efficiency over the respective free enzymes.
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ورودعنوان ژورنال:
- Chemical communications
دوره 51 71 شماره
صفحات -
تاریخ انتشار 2015